The appearance of this disorder is usually during adolescence. Familial multiple lipomatosis is inherited as an autosomal dominant trait. Several disorders are characterized by the development of benign growths (non-cancerous) consisting of adipose tissue (lipomas) including Proteus syndrome, PTEN harmatome syndrome and Gardner's syndrome. . These disorders often have additional symptoms that can distinguish them from Dercum's disease.
Lipomas are soft, greasy lumps that grow under the skin. They are harmless and do not usually need treatment. Your general practitioner will usually be able to tell if the mass is a lipoma. If there is any doubt, they can refer you to a scan to check it. In rare cases, pieces under your skin may be a sign of something more serious. Lipomas are harmless. They are not usually treated on the NHS.
There are also variants such as angiolipomas, neomorphic lipomas, fusiform cell lipomas and adenolipomas. Most lipomas are best left alone, but fast-growing or painful lipomas can be treated with a variety of procedures ranging from steroid injections to tumor excision. . Lipomas must be distinguished from liposarcoma, which may look similar. Lipomas are slow-growing, almost always benign fat tumors that are most commonly found in subcutaneous tissues.
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